氨磺必利辅以无抽搐电休克治疗精神分裂症的疗效评价

Evaluation of the Efficacy of Amisulpride Combined With No Convulsive Electroshock in the Treatment of Schizophrenia

目的观察氨磺必利辅以无抽搐电休克治疗精神分裂症的疗效。方法我院2018年5月-2019年5月收治的74例精神分裂症患者为本次研究对象,按照是否行氨磺必利辅以无抽搐电休克治疗将所有患者分为对照组(37例:未辅以无抽搐电休克治疗)与试验组(37例:辅以无抽搐电休克治疗),比较两组患者预后。结果试验组患者治疗3个疗程后总有效率(75.68%)、神经元特异性烯醇化酶(neuron specific enolase,NSE)、髓鞘碱性蛋白(myelin basic protein,MBP)、泌乳素等相关数值均优于对照组(P<0.05)。结论精神分裂症患者氨磺必利辅以无抽搐电休克治疗效果明显优于单一氨磺必利治疗。

Objective To observe the efficacy of amisulpride combined with no convulsive electroshock in the treatment of schizophrenia.Methods 74 schizophrenic patients admitted to our hospital from May 2018 to May 2019 were studied.All patients were divided into control group(37 cases:without convulsive electroconvulsive therapy)and experimental group(37 cases:with convulsive electroconvulsive therapy),and the prognosis was compared between the two groups.Results The total effective rate(75.68%)and the related values of NSE,MBP and prolactin in the experimental group were better than those in the control group(P<0.05).Conclusion The therapeutic effect of amisulpride combined with electroconvulsive therapy in schizophrenic patients is better than that of amisulpride alone.