CA153在乳腺癌免疫治疗中的作用

The role of CA153 in breast cancer immunotherapy

乳腺癌是女性常见的恶性肿瘤,免疫治疗是临床上取得较好效果的治疗手段之一。CA153可在乳腺癌免疫应答中作为特异性抗原激活免疫应答;参与T细胞活化;靶向结合多肽疫苗,增强免疫应答;诱导树突状细胞成熟,清除体内癌细胞等。因此CA153在乳腺癌的免疫应答和治疗中具有重要的作用,可作为乳腺癌免疫治疗的新靶点。

Breast cancer is a common malignant tumor in women,and immunotherapy is one of the treatments with a good clinical prognosis.CA153 can activate immune response as a specific antigen in breast cancer immune response;participate in T cell activation;target binding peptide vaccine;enhance immune response;induce dendritic cell maturation,and eliminate cancer cells in vivo.Therefore,CA153 plays an important role in the immune response and treatment of breast cancer,and can be used as a new target for breast cancer immunotherapy.