西甲硅油联合布拉氏酵母菌治疗婴儿肠绞痛的临床疗效观察

Clinical Efficacy of Simethicone Combined with Bradyr’s Yeast in the Treatment of Infantile Colic

目的观察西甲硅油联合布拉氏酵母菌治疗婴儿肠绞痛的临床疗效。方法选择2018年5月—2019年4月于惠阳三和医院治疗的100例肠绞痛患儿,按随机数表法平分为两组。对照组接受腹部按摩及安慰处理,观察组在对照组基础上加用西甲硅油、布拉氏酵母菌治疗。对比两组治疗效果、治疗前后发作哭闹时间、复发率及不良反应等。结果观察组总有效率(90.00%)高于对照组(60.00%),复发率(8.00%)低于对照组(30.00%),差异有统计学意义(P<0.05);治疗前两组哭闹时间对比,差异无统计学意义(P>0.05);治疗后观察组哭闹时间(32.65±14.76)min短于对照组(98.41±13.87)min,差异有统计学意义(P<0.05);两组患儿均未见严重不良反应,仅观察组出现口干1例,未经对症处理消失。结论肠绞痛患儿接受西甲硅油、布拉氏酵母菌联合治疗安全性、有效性较高,利于加快患儿症状缓解,减少复发率。

Objective To observe the clinical efficacy of simethicone combined with Bradyr’s yeast in the treatment of infantile colic.Methods 100 children with colic in the hospital from May,2018 to April,2019 were enrolled.The patients were divided into two groups,with 50 cases in each group.The control group received abdominal massage and comfort treatment.The observation group were treated with simethicone and Brahiliella on the basis of the control group.The effects of the two groups were compared,including the time of crying,the recurrence rate and adverse reactions before and after treatment.Results The total effective rate of the observation group(90.00%)was higher than that of the control group(60.00%),and the recurrence rate(8.00%)was lower than that of the control group(30.00%).The difference was statistically significant(P<0.05).There was no statistically significant difference between the two groups(P>0.05).After treatment,the observation group crying time(32.65±14.76)min was shorter than the control group(98.41±13.87)min.The difference was statistically significant(P<0.05).Neither group had serious symptoms.Only one case had dry mouth in the observation group,and disappeared without symptomatic treatment.Conclusion Treatment of the combination of simethicone and bacillus on children with colic is safe and effective.It is helpful for accelerating symptom relief and reducing recurrence rate.