老年2型糖尿病营养状况与臂踝脉搏波传导速度的相关性研究

Research on the relationship between nutritional status and brachial-ankle pulse wave velocity in elderly patients with type 2 diabetes mellitus

目的探讨老年2型糖尿病住院患者营养不良参数与臂踝脉搏波传导速度(baPWV)的关系。方法 158例老年2型糖尿病住院患者按微型营养评定法(MNA)分为营养良好组、营养不良风险组、营养不良组。各组患者均行baPWV及相关生化指标检测。结果营养不良组较营养良好组和营养不良风险组baPWV升高。且随着营养状况的下降,baPWV逐渐增高。Pearson相关分析显示,MNA评价、血红蛋白、血清白蛋白、血清前白蛋白和体重指数与baPWV呈负相关(P <0.05)。多变量Logistic回归分析结果显示,仅MNA、血清前白蛋白与baPWV升高相关。结论老年2型糖尿病营养状况与baPWV相关,营养不良患者动脉硬化病变较严重。

Objective To investigate the relationship between the nutritional status and baPWV in elderly type 2 diabetic patients. Methods A total of 158 subjects were enrolled and divided into good nutrition group, risk of malnutrition group and malnutrition group by Mini Nutritional Assessment(MNA). Brachial ankle pulse wave velocity and related biochemical indexes were measured. Results The baPWV in the elderly type 2 diabetic malnutrition group was significantly higher than that in the well-nourished group and the malnutrition risk group. With the decrease of nutritional status, the baPWV increased gradually. Pearson correlation analysis showed that baPWV was negatively correlated with MNA, hemoglobin, serum albumin, serum prealbumin and body mass index. Multivariate logistic regression analysis showed that only MNA and serum prealbumin were associated with increased baPWV. Conclusions The nutritional status of type 2 diabetes mellitus in the elderly is related to its baPWV levels, and atherosclerotic lesions are more serious in malnutrition patients.