马方综合征致缺血性卒中一例

Ischemic stroke caused by Marfan syndrome: a case report

马方综合征是一种常见的结缔组织疾病,患者可以出现心血管、眼部、骨骼体征,而合并脑梗死较少见,也是不明原因青年卒中少见病因的一种,早期的心脏彩色多普勒超声及全面的血管评估有助于提高临床诊断和治疗效果,早期干预可获得良好预后和生活质量。作者回顾性分析1例基因确诊的马方综合征导致的缺血性卒中的临床资料,并结合相关文献,分析探讨了马方综合征导致血管事件的可能原因。

Marfan syndrome is a common connective tissue disease with cardiovascular,ocular and skeletal menifestations,but combination with cerebral infarction is rare.Marfan syndrome is also a rare cause of youth stroke with undetermined cause.Early cardiac color doppler ultrasound and comprehensive vascular assessment can improve clinical diagnosis and treatment effect,and early intervention can obtain the good prognosis and life quality of patients.A case of ischemic stroke caused by Marfan syndrome was reported in this article.Combined with relevant literature,the possible mechanisims of vascular events associated with Marfan syndrome was analyzed.