中医状态指导下的糖组学应用探讨

Discussion on the Application of Glycomics under the Guidance of Traditional Chinese Medicine

状态是结构与功能、时间与空间的统一体,状态在外界因素刺激下,可以通过脏腑、经络、气血等作出相应的反应。人的状态分为未病状态、欲病状态、已病状态、病后状态4种。文章通过文献梳理,探讨系统生物学中糖组学研究方法在中医疾病状态下的应用,以期在系统论、整体论的思维指导下,运用糖组学技术,寻找疾病状态下的特异性糖组、阐释中医状态的物质基础、丰富中医状态的微观参数采集方法、建立微观辨识模型。

State is the unity of structure and function,time and space.Under the stimulation of external factors,the state can respond accordingly through organs,meridians,qi and blood.The state of the person is divided into four categories:untreated state,ill-conditioned state,diseased state,and post-ill state.In this paper,we use the literature to explore the application of glycoomics research methods in system biology under the condition of TCM disease,in order to use the glycosics technology to find specific glycans under disease conditions under the guidance of system theory and holistic thinking.Explain the material basis of the state of TCM,enrich the microscopic parameters of TCM state,and establish a micro-identification model to make certain contributions.