控液手册联合补偿策略对腹膜透析患者容量状态及残余肾功能的影响

Effects of liquid control manual combining with compensation strategy on volume status and residual renal function in patients undergoing peritoneal dialysis

目的探讨控液手册联合补偿策略对腹膜透析患者容量状态及残余肾功能的影响。方法将120例腹膜透析患者按照随机数字表法分为对照组和观察组各60例。对照组给予常规护理,观察组在常规护理基础上应用控液手册联合补偿策略。比较两组干预前、干预6个月后的收缩压、舒张压、体质量、24h尿量、超滤量、水肿程度、血尿素氮、血肌酐、尿素清除指数、肌酐清除率、肾小球滤过率(eGFR)。结果干预后,观察组收缩压、舒张压、体质量显著低于对照组,尿量显著多于对照组,水肿程度显著轻于对照组,血尿素氮、血肌酐检测值显著低于对照组,尿素清除指数及肾小球滤过率显著高于对照组(P<0.05,P<0.01)。结论控液手册联合补偿策略有利于改善患者的容量超负荷状况,延缓残余肾功能下降。

Objective To explore the effects of liquid control manual combining with compensation strategy on volume status and residual renal function in patients undergoing peritoneal dialysis.Methods Totally 120patients undergoing peritoneal dialysis were randomized into a control group and an experimental group using a randomized digital table,with 60cases in each group.The control group received routine care,while the experimental group additionally received the liquid control manual combining with compensation strategy.The systolic blood pressure,diastolic blood pressure,body weight,24hours urinary output,ultrafiltration,edema degree,urea nitrogen,serum creatinine,urea clearance index,creatinine clearance and glomerular filtration rate before the intervention and 6 months after the intervention were compared between the two groups.Results After the intervention,the systolic blood pressure,diastolic blood pressure and body weight of the experimental group were significantly lower than those of the control group,the 24hours urinary volume was significantly more and the edema degree was significantly milder,and urea nitrogen and creatinine testing value were significantly lower,while urea clearance index and glomerular filtration rate were significantly higher than those of the control group(P<0.05,P<0.01).Conclusion The liquid control manual combining with compensation strategy is beneficial to improve the condition of volume overload for patients undergoing peritoneal dialysis,and delay the decline of residual renal function.