淫羊藿苷对成骨细胞/软骨细胞作用机制研究

Study on the Mechanism of Icariin on Osteoblasts/Chondrocytes

淫羊藿(又称仙灵脾)为小檗科淫羊藿属植物淫羊藿的干燥茎叶,具有补肾阳、强筋骨、祛风湿等功效,是被广泛应用的补益类传统中草药之一。淫羊藿苷是淫羊藿的主要有效单体活性成分和药材质量评价指标,近年亦有大量关于其对促成骨作用及机制等诸多系统疾病具有防治作用,对新近有关淫羊藿苷对促成骨相关主要细胞作用机制研究现状进行综述,为进一步的临床应用和实验研究提供理论依据。

yínyánghuò(also known as xiānlíngpí)in chinese herbal medicine is the dried stem and leaf of Epimedium brevicornum Max,As the effects of strengthening with tonics,supplement the kidney Yang,strength sinew and bone,dispel wind-damp.it is widely used as a tonic medicine in the traditional chinese medicine.Icariin is the main active component of yínyánghuò monomer and the quality evaluation index of yíny nghu,In current yeas,the scientist have been conducted tremendous fundamental studies to research the pharmacological activities of Icariin,to reveal its protective effects on the bone action and its mechanism,central nervous system as well as to many other aspects. It is hoped that the relevant study about the pharmacological action of icariin would help its further clinical application and experimental research.