主动脉瘤腔内修复术后综合征的危险因素分析

Post-endovascular aortic repair syndrome: risk factor analysis of endovascular aneurysm repair

目的探讨主动脉瘤腔内修复术(endovascular aneurysm repair,EVAR)后早期不良事件的危险因素。方法通过对1997-2014年于我院就诊的2193例主动脉瘤患者临床资料进行回顾性研究,运用多因素Logistic回归分析出现EVAR术后早期不良事件(early postoperative adverse events,EPAE)患者的围手术期血液学指标。结果术后早期不良事件的发生率为20.8%。多因素Logistic回归分析结果显示,术后白细胞计数(OR=1.24,95%CI:1.06-1.16,P=0.008)、血红蛋白水平(OR=0.87,95%CI:0.83-0.92,P<0.001)和血小板水平(OR=0.99,95%CI:0.98-1.00,P=0.029)的优势比有统计学意义。结论术后白细胞升高、血红蛋白下降和血小板下降是与EPAE相关的独立危险因素。

Objective To investigate the risk factors for early postoperative adverse events(EPAE)after endovascular aneurysm repair(EVAR).Methods A total of 2193 cases of aortic aneurysm treated in Changhai Hospitaly from 1997 to 2014 were analyzed retrospectively.The perioperative hematological variables in relation to EPAE after EVAR were analyzed.Results The rate of EPAE was 20.8%.Multivariate analysis showed postoperative white cell count(OR=1.24,95%CI:1.06-1.16,P=0.08),hemoglobin level(OR=0.87,95%CI:0.83-0.92,P<0.01),and platelet level(OR=0.99,95%CI:0.98-1.00,P=0.029)to be independent factors associated with the EPAE.Conclusion Increased white cell count and decreased hemoglobin and platelet levels are independent risk factors for EPAE.