肝素联合阿司匹林治疗复发性流产的研究

Study of heparin combined with aspirin in the treatment of recurrent abortion

为了进一步对抗磷脂抗体引起的复发性流产给予治疗,医学界开始深度研究多种药物的联合应用,借助不同使用指征和方法提升治疗效果。目前,肝素联合阿司匹林治疗抗磷脂抗体引起的复发性流产是国际上较为常见且应用广泛的治疗方案,能有效提升患者的预后效果,从根本上构建完整的研究机制,一定程度上实现较好的整体治疗效果。本文从抗凝作用、抑制补体活性、滋养细胞三个方面分析了肝素和阿司匹林治疗抗磷脂抗体引起的复发性流产的作用机制和治疗优势,并对两种药物的联合应用给予讨论,集中阐释了研究过程和具体的应用路径,以供临床参考。

In order to further treat recurrent abortion caused by antiphospholipid antibodies, the medical community begins to deeply study the combined application of various drugs, and improve the therapeutic effect by different indications and methods. Currently, heparin combined with aspirin is used to treat recurrent abortion caused by antiphospholipid antibodies, which is a relatively common and widely used treatment programme in the world. It can effectively improve the prognosis effect of patients, and fundamentally construct a complete research mechanism to achieve a better overall treatment effect to a certain extent. In this paper, the mechanism and therapeutic advantages of heparin and aspirin in the treatment of recurrent abortion caused by antiphospholipid antibodies are analyzed from three aspects: anticoagulation, inhibition of complement activity and trophoblastic cells. The combined application of the two drugs is discussed, and the research process and specific application paths are explained for clinical reference.