CEUS检查对乙型肝炎病毒肝硬化合并小肝癌患者早期诊断准确率的影响

Effect of CEUS examination on early diagnosis accuracy of patients with liver cirrhosis complicated with small liver cancer

目的探究超声造影(CEUS)在肝硬化合并小肝癌早期诊断中的应用价值。方法肝硬化合并肝内结节样病灶患者135例,分别采用CEUS与增强螺旋CT(CECT)进行诊断,所有患者进行穿刺活检或手术病理结果为金标准,评估两种检查方法对肝硬化合并小肝癌的诊断效能。结果联合检测灵敏度、特异度及准确度均显著高于各单项检测(P<0.05),CEUS的灵敏度及准确度均显著高于CECT(P<0.05),而CEUS的特异度显著低于CECT(P<0.05)。结论 CEUS与CECT在肝硬化合并小肝癌评测中具有较高的临床诊断价值,其中CEUS诊断价值较高,二者联合检测诊断效能最高,可为肝硬化合并小肝癌临床诊治提供参考。

Objective To explore the value of contrast-enhanced ultrasound(CEUS) in the early diagnosis of cirrhosis with small hepatocellular carcinoma.Methods A total of 135 patients with cirrhosis and intrahepatic nodular lesions were enrolled.CEUS and contrast-enhanced helical computed tomography(CECT) were used for diagnosis.All patients underwent needle biopsy or surgical pathology as the gold standard,and the diagnostic efficacy of the two methods for cirrhosis with small liver cancer was evaluated.Results The sensitivity,specificity and accuracy of the combined detection were significantly higher than the individual tests(P<0.05).The sensitivity and accuracy of CEUS were significantly higher than CECT(P<0.05),while the specificity of CEUS was significantly lower than that of CECT(P<0.05).Conclusion The combination of the two has the highest diagnostic efficiency,which can provide reference for the clinical diagnosis and treatment of cirrhosis with small liver cancer.