补体系统在阿尔茨海默病中的研究进展

Progress of complement system in Alzheimer’s disease

阿尔茨海默病(AD)是一种日益增长的全球性疾病,对个人和社会都有着巨大的影响。本文旨在阐述补体系统在AD不同发病机制中的最新研究进展,并对目前的临床实验室诊断方法进行了讨论。同时为寻求AD的生物标志物及疾病的早期干预提供理论依据及新思路。

Alzheimer’s disease(AD)is a growing global health concern with huge implications for individuals and society.In this review,current understanding of the pathogenesis of complement system in Alzheimer’s disease is outlined and current clinical laboratory diagnostic methods are discussed.Some theoretical basis and new ideas for seeking the biomarkers of AD and its treatment are also provided.