亚临床甲状腺功能减退症合并急性脑梗死的诊治分析

Diagnosis and treatment of subclinical hypothyroidism complicated with acute cerebral infarction

目的分析亚临床甲状腺功能减退症(亚临床甲减)对急性脑梗死的影响。方法选取医院收治的亚临床甲减合并急性脑梗死患者50例为亚临床甲减组,另选取同期无甲状腺疾病的脑梗死患者50例为对照组。比较2组甲状腺功能、血糖、血脂、血同型半胱氨酸和纤维蛋白原水平及颈部血管彩色超声检查结果。结果亚临床甲减组GLU、Hcy、FT3、FT4和TSH水平高于对照组,差异均有统计学意义(P<0.05)。亚临床甲减组TC、LDL-C、TG水平高于对照组,差异均有统计学意义(P<0.05)。亚临床甲减组不稳定斑块发生率及颈动脉狭窄发生率均高于对照组,差异有统计学意义(P<0.05)。结论亚临床甲减可能是脑梗死的危险因素之一。

Objective To analyze the effect of subclinical hypothyroidism on acute cerebral infarction.Methods 50 patients with subclinical hypothyroidism combined with acute cerebral infarction were selected as subclinical hypothyroidism group,another 50 patients with cerebral infarction without thyroid disease were selected as the control group.The thyroid function,blood glucose,blood lipids,blood homocysteine and fibrinogen levels and cervical vascular color ultrasonography were compared between the two groups.Results The levels of GLU,Hcy,FT3,FT4 and TSH in the subclinical hypothyroidism group were higher than those in the control group(P<0.05).The levels of TC,LDL-C and TG in the subclinical hypothyroidism group were higher than those in the control group,and the differences were statistically significant(P<0.05).The incidence of unstable plaque and the incidence of carotid stenosis in the subclinical hypothyroidism group were higher than those in the control group(P<0.05).Conclusion Subclinical hypothyroidism may be one of the risk factors of acute cerebral infarction.