锡类散在治疗糖尿病患者口腔溃疡中与其他药物联合应用的效果观察

The Effect Observation of Combined Application of Tin-like Powder with Other Drugs and in theTreatment of Diabetic Patients with Oral Ulcer

目的:探讨糖尿病患者口腔溃疡应用双氧水及丁卡因凝胶联合锡类散喷剂的治疗效果。方法:将98例糖尿病并发口腔溃疡患者随机分为实验组(49例)、对照组(49例),分别采用双氧水及丁卡因凝胶联合锡类散喷剂和单独应用锡类散喷剂两种不同方法治疗5d,随访两周,进行对比观察。结果:实验组患者的治疗总有效率(95.9%)明显高于对照组(81.6%),两组比较,差异具有统计学意义(P<0.01);实验组口腔溃疡疼痛缓解时间及溃疡愈合时间明显低于对照组,差异具有统计学意义(P<0.01)。结论:双氧水及丁卡因凝胶联合锡类散喷剂治疗糖尿病患者口腔溃疡总有效率更高,治疗效果更快,值得推广应用。

Objective: To investigate the effect of tin-like powder combined H2O2 and Tetracaine gel in the treatment of diabetic patients with oral ulcer. Methods: 98 diabetic patients with oral ulcer were randomized into treatment group(n=49) and control(n=49). The treatment group was treated with tin-like powder combined with H2O2 and Tetracaine gel and the control group only with tin-like powder. All the patients were treated for 5 days,subsequently two weeks’ follow-up, then clinical effect was compared between the two groups. Results: The total effective rate of oral ulcer in treatment group(95.9%) is obviously higher than that of the control group(81.6%),the difference was statistically significant(P<0.01). Meanwhile the time of pain relief and ulcer healing is obviously shortened, with the difference statistically significant(P<0.01). Conclusion: In the treatment of oral ulcer with diabetes, combination of tin-like powder, H2O2 and Tetracaine gel has higher effective rate and more rapid curative effect, therefore it is worthy of clinical application.