分析磷酸奥司他韦治疗小儿季节性流感的疗效及对炎症因子的影响被引量：6

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摘要目的分析磷酸奥司他韦治疗小儿季节性流感的疗效及对炎症因子的影响.方法126例小儿季节性流感患儿为研究对象,随机分为对照组与观察组,各63例.对照组患儿给予口服小儿豉翘清热颗粒进行治疗,观察组患儿给予口服磷酸奥司他韦进行治疗.比较两组患儿的临床疗效,治疗前后的C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)及干扰素-γ(IFN-γ)炎症因子水平.结果治疗后,观察组患儿的总有效率为95.24%,高于对照组的80.95%,差异具有统计学意义(P<0.05).治疗前,两组患儿的CRP、TNF-α及IFN-γ炎症因子水平比较,差异均无统计学意义(P>0.05);治疗后,观察组患儿的CRP、TNF-α及IFN-γ炎症因子水平均低于对照组,差异均具有统计学意义(P<0.05).结论磷酸奥司他韦用于治疗小儿季节性流感能有效的提升临床疗效,降低炎症因子水平.

作者阮金德

机构地区深圳市宝安区石岩人民医院儿科

出处《中国现代药物应用》 2019年第24期159-161,共3页 Chinese Journal of Modern Drug Application

关键词磷酸奥司他韦小儿季节性流感炎症因子临床疗效

分类号 R72 [医药卫生—儿科]

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