隐源性机化性肺炎及继发性机化性肺炎的临床特征及影像特点分析

Clinical characteristics and imaging characteristics of cryptogenic organizing pneumonia and secondary organizing pneumonia

目的:分析研究隐源性机化性肺炎与继发性机化性肺炎患者的临床特征及影像学特点。方法:回顾性分析33例隐源性机化性肺炎及34例继发性机化性肺炎患者的临床资料,对比观察两组患者的临床特征及影像学特征。结果:隐源性机化性肺炎患者发热比例更低,与继发性机化性肺炎比较,差异有统计学意义(P<0.05);患者多伴有湿罗音和爆裂音;两组患者均出现C反应蛋白上升,但两组患者对比差异无统计学意义(P>0.05);两组患者白细胞、中性粒细胞、血红蛋白、白蛋白及总蛋白对比差异无统计学意义(P>0.05);两组患者均出现低氧血症(PaO2降低),但两组患者对比差异无统计学意义(P>0.05);两组患者PaO2、HCO3-及pH值对比差异无统计学意义(P>0.05);隐源性机化性肺炎影像学结果显示胸腔积液发生率较低,与继发性机化性肺炎比较,差异有统计学意义(P<0.05)。结论:隐源性机化性肺炎与继发性机化性肺炎患者的临床特征及影像学特点差异性较小,但是隐源性机化性肺炎多体温正常,胸腔积液发生较少,可用于临床鉴别。

Objective:To analyze the clinical features and imaging features of patients with cryptogenic organizing pneumonia and secondary organizing pneumonia,and to provide clinical reference.Methods:The clinical data of 33 patients with cryptogenic organizing pneumonia and 34 patients with secondary organizing pneumonia admitted from January 2012 to January 2019 in our hospital were retrospectively analyzed.Results:The proportion of patients with cryptogenic organizing pneumonia was higher,compared with secondary organizing pneumonia,the difference was statistically significant(P<0.05);patients were often accompanied by wet rales and popping sounds;both groups of patients showed C reactive protein rise;there were no significant differences in white blood cell,neutrophil,hemoglobin,albumin and total protein between the two groups(P>0.05).Hypoxemia(lower PaO2)occurred in both groups,but there was no difference between the two grupes(P>0.05);There was no significant difference in PaO2,HCO3-and PH values between the two groups(P>0.05);the imaging results of cryptogenic organizing pneumonia showed a higher incidence of pleural effusion,compared with secondary organizing pneumonia,the difference was statistically significant(P<0.05).Conclusions:The clinical features and imaging features of patients with cryptogenic organizing pneumonia and secondary organizing pneumonia are small,but cryptogenic organizing pneumonia has normal body temperature and less pleural effusion,which can be used in clinical practice for identification.