胆道癌免疫疗法的现状及展望

Immunotherapy for biliary tract cancer: Current status and perspectives

胆道癌在临床上较为少见,早期诊断困难,常规治疗手段疗效欠佳。作为时下新兴的研究热点,免疫疗法已被证实在多种癌症治疗中具备良好前景。目前包括免疫检查点抑制剂、过继免疫细胞治疗、肿瘤疫苗等在内的多种免疫疗法已经被运用于胆道癌的相关临床试验治疗中。现就免疫疗法在胆道癌治疗中的现状及展望进行简要阐述。

Biliary tract cancer(BTC)is rare in clinical practice and is difficult to diagnose in the early stage,and conventional treatment methods have unsatisfactory clinical effects.As a new research hotspot at present,immunotherapy has been proven to have a promising future in the treatment of a variety of cancers.At present,various immunotherapies,including immunological checkpoint inhibitors,adoptive immune cell therapy,and tumor vaccine therapy,have been applied in the clinical trials of BTC.This article briefly describes the current status and perspectives of immunotherapy in the treatment of BTC.