高龄腔隙性脑梗死患者脑白质疏松与肾小球滤过率的相关性分析

Correlation between leukoaraiosis and glomerular filtration rate in elderly patients with lacunar infarction

目的:分析高龄腔隙性脑梗死(LI)患者脑白质疏松(WMH)与肾小球滤过率(GFR)之间的相关性.方法:收治高龄LI患者63例,对临床资料、病历资料进行回顾性分析,分析WMH与GFR之间相关性.结果:WMH轻度组血清肌酐水平明显低于重度组,GFR明显高于重度组,差异均有统计学意义(P<0.05).结论:提示GFR与WMH存在负相关,GFR可以作为反映高龄LI患者WMH严重程度的临床指标.

Objective:To explore the correlation between leukoaraiosis(WMH)and glomerular filtration rate(GFR)in elderly patients with lacunar infarction(LI).Methods:63 elderly patients with LI were selected,the clinical data and medical records were analyzed retrospectively,we analyzed the correlation between WMH and GFR.Results:The serum creatinine level of the WMH mild group was significantly lower than that of the severe group,and GFR was significantly higher than that of the severe group,the difference was statistically significant(P<0.05).Conclusion:GFR had a negative correlation with WMH,GFR can be used as a clinical indicator to reflect the severity of WMH in elderly LI patients.