上颌窦容积与真菌球型上颌窦炎的相关性

The correlation between maxillary sinus volume and fungal ball maxillary sinusitis

目的分析真菌球型上颌窦炎患者上颌窦容积、中鼻道容积、上颌窦骨壁厚度的临床特征,探讨上颌窦容积与真菌球型上颌窦炎发生的相关性。方法选取44例真菌球型上颌窦炎患者(病例组)和31例正常人(正常组)进行CT扫描,采用3D应用软件放大镜技术测量出病例组与正常组的双侧上颌窦骨壁厚度,应用Volume处理软件各层面积叠加计算出各组上颌窦容积、中鼻道容积,并计算出中鼻道/上颌窦容积比,对测量的结果进行统计学分析。结果病例组与正常组的上颌窦骨壁厚度、中鼻道容积比较,差异有统计学意义(t值分别为12.936、2.107,均P <0.05)。而上颌窦容积、中鼻道/上颌窦容积比差异无统计学意义(P> 0.05)。真菌球型上颌窦炎患者双侧上颌窦骨壁厚度、上颌窦容积相比较,患侧上颌窦骨壁厚度更大,上颌窦容积更小,两组差异有统计学意义(t值分别为8.914、2.028,均P <0.05)。而中鼻道容积、中鼻道/上颌窦容积比差异无统计学意义(P> 0.05)。病例组上颌窦容积与上颌窦骨壁厚度的Pearson相关系数为-0.157,P=0.310;上颌窦容积与中鼻道容积Pearson相关系数为-0.076,P=0.622。结论上颌窦容积解剖学基础可能与真菌球型上颌窦炎的发生有关,真菌感染时容易在容积更小的一侧形成真菌球。

Objective To analyze the clinical characteristics of maxillary sinus volume,middle meatus volume and maxillary sinus wall thickness in patients with fungal ball maxillary sinusitis,and to explore the potential correlation between maxillary sinus volume and fungal ball maxillary sinusitis. Methods A total of 44 patients with fungal ball maxillary sinusitis were enrolled for CT scan,and 31 healthy subjects were also selected as normal control. The thicknesses of bilateral maxillary sinus bone wall in each group was measured by magnifying glass technology using 3D application software. The volumes of the maxillary sinus and middle meatus in each group were calculated by superimposing each layered area using Volume software. The volume ratios of middle meatus/maxillary sinus were evaluated. The above measurement results were further statistically analyzed. Results There were significant differences in middle meatus volume and the thickness of maxillary sinus bone wall between the fungal ball maxillary sinusitis group and normal control group(t values were 12.936 and 2.107,respectively,both P < 0.05). However,there was no significant difference in either maxillary sinus volume or the volume ratio of middle meatus/maxillary sinus(P > 0.05). The thicknesses of maxillary sinus bone wall was larger and the volume of the maxillary sinus was smaller in the affected sides when compared with the other sides in patients with fungal ball maxillary sinusitis(t values were 8.914 and 2.028,respectively,both P < 0.05). There was also no significant difference in the volume of the middle meatus and the volume ratio of middle meatus/maxillary sinus(P > 0.05).The Pearson correlation coefficient between the maxillary sinus volume and the maxillary sinus bone thickness in the patients with fungal ball maxillary sinusitis was-0.157,P = 0.310;the Pearson correlation coefficient between the maxillary sinus volume and the middle meatus volume was-0.076,P = 0.622. Conclusion There may be a correlation between the occurrence of fungal ball maxillary sinusitis and the anatomical basis of maxillary sinus volume,and the fungal ball is more likely to be formed on the side of the maxillary sinus with a smaller volume.