双歧三联活菌治疗肝硬化患者的疗效及对肠道菌群的影响

Effect of Bifid Triple Viable Bacteria and its influence on intestinal flora in patients with liver cirrhosis

目的 探讨双歧三联活菌治疗肝硬化患者的疗效及对肠道菌群的影响.方法 选取116例肝硬化患者为研究对象,将采取常规综合治疗的患者设为对照组(n=58),加用双歧三联活菌治疗者设为研究组(n=58),观察2组患者肝硬化疗效、肠道菌群变化.结果 研究组患者肝硬化整体有效率显著高于对照组(P<0.05);治疗后,研究组需氧菌、厌氧菌水平均显著高于对照组,酵母样真菌水平显著低于对照组(P<0.05).结论 双歧三联活菌可优化肝硬化患者的治疗效果,纠正肠道菌群紊乱.

Objective To investigate the effect of Bifid Triple Viable Bacteria and its influence on intestinal flora in patients with liver cirrhosis.Methods A total of 116 patients with liver cirrhosis in our hospital were selected and were divided into two groups.The control group(n=58)was given routine comprehensive treatment,and the study group(n=58)was additionally given Bifid Triple Viable Bacteria therapy.The changes of intestinal flora,and efficacy of liver cirrhosis were analyzed.Results The overall effective rate of liver cirrhosis in the study group was higher than that in the control group(P<0.05).After treatment,the levels of aerobic and anaerobic bacteria in the study group were higher and yeast-like fungi level was lower than that in the control group(P<0.05).Conclusion Bifid Triple Viable Bacteria can optimize special treatment efficacy of liver cirrhosis and correct intestinal flora disorder.