内镜黏膜下剥离术后溃疡愈合影响因素的研究进展

Research progress on influencing factors of ulcer healing after endoscopic submucosal dissection

内镜黏膜下剥离术(endoscopic submucosal dissection,ESD)作为消化道早癌及癌前病变的标准治疗方式已被广泛接受,相较于传统手术,有微创、显效、美观、并发症少等优点。ESD术后溃疡是指ESD后创面形成的医源性溃疡,可导致狭窄、穿孔、出血等并发症,严重者需再次行内镜下治疗或转外科进行手术治疗。本文就ESD术后溃疡愈合的相关影响因素及药物治疗作一概述。

Endoscopic submucosal dissection(ESD)has been widely accepted as a standard treatment for gastrointestinal early cancer and precancerous lesions.Compared with traditional surgery,it has the advantages of minimally invasive,obvious effect,beautiful appearance and less complications.Ulcers after ESD are iatrogenic ulcers formed after endoscopic submucosal exfoliation,which can cause complications such as stenosis,perforation,bleeding and so on.Severe cases need to be treated by re-endoscopy or transferred to surgery for surgical treatment.This article reviewed the related influencing factors and drug treatment of ulcer healing after ESD.