有机合成中“官能团添加策略”的教学思考

Ponder on Teaching Method of Syntheses Strategy of Functional Group Addition

官能团的添加是有机合成中一种常见的合成策略。基础有机合成教学中,官能团的添加主要有-COOEt、C=C、C≡C、羰基和苯环上定向基团的添加等。鉴于“官能团添加策略”在有机合成中应用非常广泛,而国内有机合成的教材对此缺乏系统性的阐述,本文结合多所学校历年有机化学考研真题,通过大量实例,详细阐述了-COOEt、C=C、C≡C、羰基和苯环上定向基团的添加在有机合成中的应用。

Functional group addition is a common syntheses strategy in organic syntheses.In the teaching course of Fundamental Organic Syntheses,addition of functional groups mainly involves-COOEt,C=C,C≡C,carbonyl group and orientation groups on benzene rings.Strategies of functional group addition are widely used in organic syntheses,but there is no systematic illustration on this aspect.Functional group addition strategy of above-mentioned functional groups was comprehensively expounded in conjunction with real questions from postgraduate entrance exams of many universities.