利伐沙班在房颤电复律患者中的应用

Application of Rivaroxaban in atrial fibrillation patients with electrical cardioversion

目的探讨利伐沙班在房颤电复律患者中的应用效果。方法选取我院2018年3月-2019年2月期间收治的64例房颤患者,利用随机数字表法分为2组各32例。电复律后,对照组采用华法林抗凝治疗,观察组采用利伐沙班抗凝治疗,对比2组INR达标率、血栓栓塞及出血情况。结果观察组INR达标率较对照组高,差异有统计学意义(P<0.05);2组血栓栓塞发生率对比差异无统计学意义(P>0.05);观察组出血发生率较对照组低,差异有统计学意义(P<0.05)。结论在房颤电复律患者治疗中应用利伐沙班可有效提升INR达标率,降低出血发生率,值得临床推广。

Objective To investigate the application of rivaroxaban in atrial fibrillation patients with electrical cardioversion.Methods 64 patients with atrial fibrillation in the hospital from March 2018 to February 2019 were divided into two groups according to random number table,with 32 cases in each group.After electrical cardioversion,control group was given anticoagulation therapy with warfarin,while observation group was given anticoagulation therapy with rivaroxaban.The level of INR,target rate of INR,thromboembolism and bleeding were compared between the two groups.Results The target rate of INR in observation group was higher than that in control group(P<0.05),There was no statistical difference in the incidence of thromboembolism between the two groups(P>0.05).The incidence of bleeding in observation group was lower than that in control group(P<0.05).Conclusion Rivaroxaban in atrial fibrillation patients with electrical cardioversion can effectively increase the target rate of INR and decrease the incidence of bleeding,which is worthy of clinical promotion.