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The effect of porosity on the mechanical properties of 3D-printed triplyperiodic minimal surface (TPMS) bioscaffold 被引量:2

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摘要 Prevailing tissue degeneration caused by musculoskeletal maladies poses a great demand on bioscaffolds,which are artificial,biocompatible structures implanted into human bodies with appropriate mechanical properties.Recent advances in additive manufacturing,i.e.,3D printing,facilitated the fabrication of bioscaffolds with unprecedented geometrical complexity and size flexibility and allowed for the fabrication of topologies that would not have been achieved otherwise.In our work,we explored the effect of porosity on themechanical properties of a periodic cellular structure.The structure was derived from the mathematically created triply periodic minimal surface(TPMS),namely the Sheet-Diamond topology.First,we employed a series of software including MathMod,Meshmixer,Netfabb and Cura to design the model.Then,we utilized additive manufacturing technology to fabricate the cellular structures with designated scale.Finally,we performed compressive testing to deduce the mechanical properties of each cellular structure.Results showed that,in comparison with the highporosity group,the yield strength of the low-porosity group was 3 times higher,and the modulus was 2.5 times larger.Our experiments revealed a specific relationship between porosity and Young’s modulus of PLA-made Sheet-Diamond TPMS structure.Moreover,it was observed that the high-and low-porosity structures failed through distinctive mechanisms,with the former breaking down via buckling and the latter via micro-fracturing.
出处 《Bio-Design and Manufacturing》 SCIE CSCD 2019年第4期242-255,共14页 生物设计与制造(英文)
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  • 1张承焱.医用高分子材料的应用研究及发展(二)[J].中国医疗器械信息,2005,11(6):17-22. 被引量:7
  • 2Derby B. Printing and prototyping of tissues and scaffolds[J]. Scie- nce,2012,338(6109) :921.
  • 3Minns R J, Bibb R, Banks R, et al. The use of a reconstructed three-dimensional solid model from CT to aid the surgical manage- ment of a total knee arthroplasty: A case study[J]. Med Eng Phys, 2003,25(6):523.
  • 4Mahaisavariya B, Sitthiseripratip K, Oris P, et al. Rapid prototy ping model for surgical planning of corrective osteotomy for cubitus varus: Report of two cases[J]. Injury Extra, 2006,37(5): 176.
  • 5Lorber B, Hsiao W, Hutchings I M, et al. Adult rat retinal gangli- on cells and glia can be printed by piezoelectric inkier printing[J]. Biofabrication, 2014,6 (1) 152.
  • 6Ricci J L, Clark E A, Murriky A, et al. Three-dimensional printing of hone repair and replacement materials: Impact on eraniefaeial sur- gery[J]. J Craniofacial Surgery, 2012,23 (1) : 304.
  • 7Mironov V, Visconti R P, Kasyanov V, et al. Organ printing: Tis- sue spheroids as building blocks[J]. Biomaterials, 2009, 30 (12) : 2164.
  • 8Billiet T, Vandenhaute M, Schelfhout J, etal. A review of trends and limitations in hydrogel-rapid prototyping for tissue engineering [J]. Biomaterials, 2012,33(26) : 6020.
  • 9Han Q, Jin W, Xiao Z, et al. The promotion of neural regeneration in an extreme rat spinal cord iniury model using a collagen scar{old containing a collagen binding neuroprotective protein and an EGFR neutralizing antibody[J]. Biomaterials,2010,31(35):9212.
  • 10Saijo H, Igawa K, Kanno Y, et al. Maxillofacial reconstruction using custom-made artificial bones fabricated by inkier printing tech- nology[J]. J Artificial Organs, 2009,12 (3) .. 200.

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