经皮冠状动脉介入时机对急性心肌梗死后左心室重构及心功能的影响研究

Investigate the Effect of Percutaneous Coronary Intervention time on Left Ventricular Remodeling and Cardiac Function after Acute Myocardial Infarction

目的探讨经皮冠状动脉介入时机对急性心肌梗死后左心室重构及心功能的影响。方法选取2018年1月至2019年6月该院收治的急性心肌梗死患者20例予以急诊经皮冠脉介入手术,设为观察组。同期选取急性心肌梗死患者20例予以择期经皮冠脉介入手术,设为参照组。对两组患者临床治疗情况及预后情况进行分析、对比。结果与参照组比较,观察组患者血浆N末端前体脑利钠肽、去甲肾上腺素、肾上腺素、血浆肾素、血浆肾素、醛固酮左室舒张末径、左室收缩末径、左房内径、左室射血分数改善幅度更大,心力衰竭发生率更低,差异均有统计学意义(P<0.05)。结论应用急诊经皮冠状动脉介入手术对急性心肌梗死进行治疗,相比择期经皮冠状动脉介入手术,对患者心室重构以及左心室功能改善更为显著,可有效降低继发性心力衰竭的发生。

Objective To investigate the effect of percutaneous coronary intervention on left ventricular remodeling and cardiac function after acute myocardial infarction.Methods Twenty patients with acute myocardial infarction were enrolled in the study.The patients underwent emergency percutaneous coronary intervention and were set as the study observation group.Another 20 patients with acute myocardial infarction were enrolled in the same time period,and the patients underwent elective percutaneous coronary intervention for the reference group.The analysis and data comparison were carried out on the clinical treatment and prognosis of the two groups of patients.Results The observation group was better than the reference group in terms of indicators.The numerical improvement of NT-proBNP,NE,E,PRA,AngⅡand ALD was greater,and the difference was larger than that of the reference group(P<0.05),statistically significant.The observation group was better in terms of cardiac function than the reference group.The numerical improvement of LVDEd,LVSEd,LAd,LVEF was greater,and the difference was larger than that of the reference group(P<0.05),statistically significant;the incidence of heart failure in the observation group The relative reference group was better,the value was lower,and the difference was larger than the reference group(P<0.05),which was statistically significant.Conclusion Emergency percutaneous coronary intervention for acute myocardial infarction is more effective than elective percutaneous coronary intervention for ventricular remodeling and left ventricular function,which can effectively reduce secondary heart failure occur.