多西他赛、奥沙利铂联合替吉奥与奥沙利铂联合替吉奥治疗晚期胃癌的临床评价

Clinical Evaluation of Docetaxel、Oxaliplatin Combined with Tiggio and Oxaliplatin Combined with Tiggio in Treatment of Advanced Gastric Cancer

目的探究多西他赛、奥沙利铂联合替吉奥(DOS)与奥沙利铂联合替吉奥(SOX)治疗晚期胃癌的效果。方法选取丹阳市第二人民医院2010年1月至2018年1月收治的晚期胃癌患者20例为此次研究对象,随机分为两组,对照组实施SOX治疗方案,实验组则给予DOS治疗方案。对比两组治疗效果及不良反应。结果实验组近期临床总有效率高于对照组(P<0.05);实验组手足综合征等不良反应发生率低于对照组(P<0.05)。结论晚期胃癌患者接受DOS与SOX治疗均可获得一定的效果,其中DOS治疗方案更优。

Objective To investigate the effect of docetaxel,oxaliplatin combined with teggio(DOS)and oxaliplatin combined with teggio(SOX)in patients with advanced gastric cancer.Methods From January 2010 to January 2018,20 patients with advanced gastric cancer were randomly assigned by double-blind method.The control group received SOX therapy,while the experimental group received DOS therapy.Treatment effect and adverse events were compared between groups.Results The total clinical effective rate of the experimental group was higher than that of the control group(P<0.05).The incidence of adverse reactions such as hand-foot syndrome in the experimental group was lower than that in the control group(P<0.05).Conclusion Patients with advanced gastric cancer can obtain certain effects by receiving DOS and SOX,among which the DOS treatment scheme is better.