雷贝拉唑联合复方铝酸铋治疗消化性溃疡的效果

Effect of Rabeprazole Combined with Compound Barium Aluminate in Peptic ulcer

目的评估雷贝拉唑联合复方铝酸铋治疗消化性溃疡的临床效果。方法选取2017年3月至2018年9月江苏省苏州市吴江区第四人民医院确诊为消化性溃疡的82例患者,根据治疗方式分为两组,每组41例。观察组以雷贝拉唑联合复方铝酸铋治疗,对照组单用雷贝拉唑治疗。对比两组患者的临床疗效。结果对照组幽门螺旋杆菌(Hp)根除率为73.17%,观察组为95.12%,组间比较差异有统计学意义(P<0.05);观察组总有效率为97.56%,对照组为75.61%,组间比较差异有统计学意义(P<0.05)。结论雷贝拉唑联合复方铝酸铋是治疗消化性溃疡的有效方式,能够有效根除幽门螺杆菌,缓解临床症状,增强胃黏膜的保护功能,促进溃疡面积的快速愈合。

Objective To evaluate the clinical effect of rabeprazole combined with compound barium aluminate in the treatment of peptic ulcer.Methods From March 2017 to September 2018,82 patients diagnosed as peptic ulcer in our hospital were divided into two groups according to different treatments,41 cases in each group.The observation group was treated with rabeprazole combined with compound bismuth aluminate,and the control group was treated with rabeprazole alone.The clinical effect of the two groups of patients was compared.Results The Hp eradication rate was 73.17%in the control group and 95.12%in the observation group.The observation group was significantly higher than the control group(P<0.05).The total effective rate of the observation group was 97.56%,and the total effective rate of the control group was 75.61.%,the observation group was significantly higher than the control group(P<0.05).Conclusion Rabeprazole combined with compound barium aluminate is an effective way to treat peptic ulcer.It can effectively eradicate Helicobacter pylori,relieve clinical symptoms,enhance the protective function of gastric mucosa,and promote the rapid healing of ulcer area.