针刺联合清脾除湿汤治疗湿热型痤疮44例

Needling and Spleen-clearing Dampness-removing Decoction in Treating 44 Cases of Acne of Wind-heat Pattern

目的:观察针刺联合清脾除湿汤治疗湿热型痤疮的临床疗效。方法:将89例痤疮患者按就诊顺序随机分为观察组44例、对照组45例,对照组服用清脾除湿汤,1剂/d水煎早晚分服。观察组在对照组治疗基础上采用针刺治疗,每周3次。2组均连续治疗3个月后观察2组临床疗效及治疗前后炎症因子水平、皮损积分和生活质量评分的变化情况。结果总有效率观察组为90.9%,对照组为75.6%2组比较差异有统计学意义(P<0.05)。肿瘤坏死因子α(TNF-α)、白细胞介素6(IL-6)、白细胞介素4(I L-4)水平治疗前后2组组内比较差异有统计学意义(P<0.05)治疗后2组组间比较差异也有统计学意义(P<0.05)。皮损积分、Qol-acne评分治疗前后2组组内比较,差异有统计学意义(P<0.05);治疗后2组组间比较差异也有统计学意义(P<0.05)。结论:针刺联合清脾除湿汤治疗湿热型痤疮患者的效果显著且患者的炎症因子水平、皮损状况和生活质量均得到显著改善。

Objective:To observe curative effects of needling and spleen-clearing dampness-removing decoction in the treatment for acne of wind-heat pattern.Methods:All 89 patients were separated into 44 cases of the observation group and 45 cases of the control group using visiting order,the control group took spleen-clearing dampness-removing decoction,one dose each day,water decocted and taking in the morning and evening.The observation group were treated by needling based on the decoction,three times each week.Both groups were treated for three consecutive months.To observe the changes of clinical effects,the levels of inflammatory factors,the scores of skin lesion and quality of life before and after treating in both groups.Results:Total effective rate of the observation group was 90.9%,higher than 75.6% of the control group,and the difference could be found between both groups(P<0.05).The difference showed statistical meaning in the levels of TNF-α,IL-6 and IL-4 within two groups before and after treating(P<0.05);the difference had statistical meaning between both groups after treating(P<0.05).There were the significant differences in the scores of skin lesion and Qol-acne within two groups before and after treating(P<0.05);the difference showed statistical meaning between both groups after treating(P<0.05).Conclusion:Needling and spleen-clearing dampness-removing decoction could gain notable effects in the treatment for acne of wind-heat pattern,and improve the levels of inflammatory factors,skin lesion and quality of life notably.