摘要
探讨复方中药制剂联合运动对高脂血症大鼠不同组织HO-1/CO系统的影响。将47只雄性SD大鼠分为对照组、复方中药制剂组、单纯运动组、运动+中药组。复方中药制剂灌胃,运动干预为跑台运动。测定标本中大鼠骨骼肌和心肌不同组织中的血红素氧合酶1(HO-1)水平、CO含量、血清T-AOC含量、骨骼肌肌内甘油三酯含量、激素敏感脂肪酶(HSL)和脂蛋白脂酶(LPL)活性。研究结果:复方中药制剂和有氧运动均可以不同程度地提高机体的总抗氧化能力、HO-1/CO系统水平以及骨骼肌脂代谢水平,高脂血症大鼠服用复方中药制剂的同时坚持有氧运动的效果更显著,有氧运动对不同组织HO/CO的刺激反应具有选择性,骨骼肌对运动的应激反应更为显著。
To explore the effect of combined exercise and compound Chinese medicine prescription on ho-1/CO system in hyperlipidemia rats.47 male SD rats were divided into control group,compound Chinese medicine prescription group,exercise group and exercise+Chinese medicine group.Compound Chinese medicine prescription was intragastric administration,sports intervention was running on platform.The levels of heme oxygenase 1(ho-1),CO,serum t-aoc and skeletal muscle triglyceride,hormone-sensitive lipase(HSL)and lipoprotein lipase(LPL)in skeletal muscle and myocardium were measured.The compound Chinese medicine prescription and aerobic exercise can improve the total antioxidant capacity,HO-1/CO system level,and skeletal muscle fat metabolism.Compound Chinese medicine prescription combined with exercise showed a more significant effect.Skeletal muscle responds more manifestly to exercise stress.
作者
田祯祥
耿青青
徐德刚
TIAN Zhen-xiang;GENG Qing-qing;XU De-gang(Zaozhuang University,Zaozhuang 277160,China;Shandong Sport University,Jinan 250001,China)
出处
《体育科学研究》
2019年第6期59-66,共8页
Sports Science Research
基金
山东省自然科学基金资助项目(ZR2014CL018)
国家民委民族研究资助项目(2018-GMD-046)
关键词
中药
HO-1
内源性CO
有氧运动
高血脂症
Traditional Chinese medicine(TCM)
HO-1
endogenous CO
aerobic exercise
hyperlipemia
