摘要
甲氧基丙烯酸酯类杀菌剂是目前全球销量最大的一类杀菌剂,其广泛应用已导致该类药剂进入并污染水体环境。大量研究表明,该类杀菌剂在较低浓度下即可对水生生物产生较高毒性,在不同层次影响水生生物的生长、发育和繁殖,对水生生态系统的安全存在风险。文章对甲氧基丙烯酸酯类杀菌剂在水体环境中的残留水平、生物富集、对水生生物的急/慢性毒性效应,以及对水生生物组织形态、酶活性与蛋白表达、基因表达等方面影响的研究进展进行了综述,并讨论了该类杀菌剂今后的生态毒理学研究重点,以期为进一步研究其对水生生物的毒性效应及作用机理,以及制定相关策略以减少该类杀菌剂对水生生态系统的风险提供依据。
Strobilurins are fungicides with the largest sales around the world currently.The wide application of strobilurins has led to its pollution in the water environment.Many studies have reported that strobilurin fungicides are highly toxic to aquatic organisms even at very low concentrations,affecting the growth,development and reproductivity of aquatic organisms at different levels,posing risk to the safety of aquatic ecosystems.In this paper,the research progress was reviewed from strobilurin fungicides’residues in water environment,bioaccumulation,as well as their acute and chronic toxic effects on aquatic organisms,and the influence on morphology,enzyme activity,protein and gene expression level of aquatic organisms.Focus on the future study in ecotoxicology of strobilurins was also discussed.The main purpose is to provide literature basis for further study on toxic effects and mechanisms of strobilurin fungicides to aquatic organisms,and developing strategies to reduce risk to aquatic ecosystems.
作者
李慧
曹芳杰
邱立红
LI Hui;CAO Fangjie;QIU Lihong(College of Science,China Agricultural University,Beijing 100193,China)
出处
《农药学学报》
CAS
CSCD
北大核心
2019年第5期831-840,共10页
Chinese Journal of Pesticide Science
基金
国家重点研发计划(2017YFD0200504)