阿奇霉素序贯疗法治疗小儿肺炎支原体肺炎的临床疗效观察

Clinical efficacy of azithromycin sequential therapy in the treatment of children with pneumonia mycoplasma pneumonia

目的探讨阿奇霉素序贯治疗儿童肺炎支原体肺炎的临床疗效.方法选取120例确诊为肺炎支原体肺炎的患儿作为研究对象.随机分为实验组和对照组,每组60例.其中对照组患儿行红霉素序贯治疗,实验组患儿行阿奇霉素序贯治疗.比较两组治疗总有效率、不良反应发生率、症状恢复时间及住院时间.结果 通过比较两组整体治疗效果,实验组比对照组具有更显著的优势(P<0.05);通过比较症状恢复时间和住院时间,实验组明显少于对照组(P<0.05);另外,通过不良反应发生率的比较,两组之间的差异不明显(P>0.05).结论阿奇霉素序贯治疗儿童肺炎支原体肺炎疗效好,无严重不良反应,具有巨大的应用价值.

Objective To investigate the clinical efficacy of azithromycin in the sequential treatment of children with Mycoplasma pneumoniae pneumonia.Methods 120 children diagnosed as Mycoplasma pneumoniae pneumonia were selected as subjects.They were randomly divided into experimental group and control group,with 60 cases in each group.Among them,the control group received sequential treatment with erythromycin,and the experimental group received sequential treatment with azithromycin.The total effective rate,incidence of adverse reactions,time to symptom recovery,and length of hospital stay were compared between the two groups.Results By comparing the overall therapeutic effects of the two groups,the experimental group had a more significant advantage than the control group(P<0.05).By comparing the recovery time and hospitalization time,the experimental group was significantly less than the control group(P<0.05);There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conelusion The sequential treatment of azithromycin for children with Mycoplasma pneumoniae has good curative effect and no serious adverse reactions.It has great application value.