孤独症治疗评定量表中文版的信度和效度检验

Reliability and validity of the Chinese version of Autism Treatment Evaluation Checklist

目的分析孤独症治疗评定量表(ATEC)中文版的信度和效度,并评价ATEC中文版评分与孤独症症状和发育水平的相关性。方法入组2016年6月-2018年12月在南京医科大学附属脑科医院就诊、符合《精神障碍诊断与统计手册(第5版)》(DSM-5)孤独症谱系障碍(ASD)诊断标准的77例儿童作为病例组,招募健康儿童71名作为对照组。采用ATEC中文版、孤独症行为量表(ABC)、儿童孤独症评定量表(CARS)、孤独症诊断访谈量表修订版(ADI-R)、Gesell发育量表评定病例组儿童的临床症状和发育水平;对照组儿童完成ATEC中文版评定。采用Cronbach’sα系数评估ATEC中文版的信度,采用ROC曲线评估其效度。结果ATEC中文版总量表及其各分量表的Cronbach’sα系数在0.750~0.787之间。ATEC中文版总量表及其分量表的敏感度在0.922~0.987之间,特异度在0.803~0.887之间,曲线下面积在0.924~0.972之间。ATEC中文版总评分与CARS和ABC总评分呈正相关(r=0.509、0.580,P均<0.01);ATEC中文版的表达/语言/沟通、社交能力、感知/认知能力分量表评分与Gesell发育量表对应分量表的发育商均呈负相关(r=-0.677、-0.383、-0.332,P均<0.01)。结论ATEC中文版具有较高的信度和效度,且其评分能反映ASD症状的严重程度及患儿发育水平。

Objective To investigate the reliability and validity of the Chinese version of Autism Treatment Evaluation Checklist(ATEC),and to evaluate the correlation of the ATEC scores and autistic symptoms and developmental level.Methods A total of 77 children with autism spectrum disorders(ASD)were enrolled from the child mental health research center of Nanjing Brain Hospital Affiliated to Nanjing Medical University from June 2016 to December 2018.All met the diagnostic criteria of Diagnostic and Statistical Manual of Mental Disorders,fifth edition(DSM-5).Meanwhile,71 healthy children were recruited as the control group.The ASD children were evaluated with the Chinese version of ATEC,Autism Behavior Checklist(ABC),Child Autism Rating Scale(CARS),Autism Diagnostic Interview-Revised(ADI-R)and Gesell Development Scale.Children in the control group were examined with ATEC.We used Cronbach'sαcoefficient to evaluate the reliability of the Chinese version of ATEC and used the ROC curve to evaluate the validity.Results Cronbach'sαcoefficients of ATEC and its subscales were 0.750~0.787.The sensitivity of ATEC and its subscales were 0.922~0.987,specificity of ATEC and its subscales were 0.803~0.887,area under the curve of ATEC and its subscales were 0.924~0.972.The total score of ATEC was positively correlated with the scores of CARS and ABC(r=0.509,0.580,P<0.01).The subscale scores of ATEC speech/language/communication,sociability,and sensory/cognitive awareness were negatively correlated with the developmental quotient of the corresponding of the Gesell Development Scale(r=-0.677,-0.383,-0.332,P<0.01).Conclusion Chinese version of the ATEC has high reliability and validity,and its score can reflect the severity of autistic symptoms and developmental level of ASD children.