影响视网膜静脉阻塞及黄斑中心视网膜厚度改变的因素分析

Risk factors for retinal vein occlusion and central retinal thickness

目的:分析不同危险因素对视网膜静脉阻塞(RVO)发病的影响,同时观察并研究不同因素对黄斑中心视网膜厚度(CRT)的影响。方法:回顾性研究。收集2016-09/2019-04我院眼科就诊的RVO患者79例79眼作为RVO组,并根据CRT是否大于369μm将其分为高CRT组(26眼)和低CRT组(53眼)。收集同时期入院拟行白内障手术患者59例59眼作为对照组。统计分析RVO发病危险因素以及影响CRT改变的因素。结果:与对照组相比,RVO组中高血压、颈动脉斑块以及高同型半胱氨酸血症有差异(P<0.05)。不同CRT分组间分析结果则显示中央部位阻塞和吸烟史有差异(P<0.05)。结论:高血压、颈动脉斑块、高同型半胱氨酸血症是RVO发病的危险因素。而中央部位阻塞以及吸烟史是影响CRT厚度改变的因素。

AIM:To analyze both the effects of different risk factors on incidence of retinal vein occlusion and the comparison of difference between risk factors of RVO subgroups.METHODS:Retrospective case control study.79 cases of patients treated were collected as RVO group.These cases were further classified into high CRT group(26 cases)and low CRT group(53 cases)according to the CRT whether it is greater than 369μm.In the same time,59 cases of patients who were conducted surgery of ophthalmology ward in our hospital were also collected.Statistical analysis of risk factors.RESULTS:After a comparison between these factors and control group,it turns out that there are statistical differences on high blood,carotid artery plaque and HHCY in RVO group(P<0.05).The analysis conducted on two CRT groups revealed that difference exist in obstruction site and smoking(P<0.05).CONCLUSION:Hypertension,carotid plaque and HHCY are risk factors of RVO.In the two CRT groups,the factors that may affect CRT are obstruction site and smoking.