兰州市某单位体检人群CAVI测定结果及相关因素分析

The analysis of the results and related factors of CAVI in the physical examination population of an enterprise in Lanzhou

目的通过检测健康体检人群心-踝血管指数(CAVI),探讨健康人群动脉粥样硬化(AS)患病率及其危险因素。方法选取在我院健康体检的兰州市某企业单位792人,测量其CAVI、体重指数、血压、血糖、血脂、尿酸及血红蛋白(HGB)、红细胞分布宽度(RDW-SD)等,询问高血压、糖尿病史、吸烟及运动等项目。根据CAVI结果分为AS组、临界组和非AS组,分组后进行组间基线资料统计、多因素回归分析,研究动脉硬化的危险因素。结果AS组的年龄、收缩压、舒张压、空腹血糖、胆固醇、红细胞分布宽度等高于临界组,临界组高于非AS组;吸烟组CAVI检出率高于非吸烟组,临界组较高;而非运动组CAVI检出率高于运动组(P<0.05)。年龄、性别、BMI、血压、血糖、RDW-SD是AS独立危险因素,其中血压对动脉硬化的影响最大(OR=4.089)。结论多种因素与AS发生有关,年龄、性别、血压、血胆固醇、血糖有关的报道很多,本研究发现RDW-SD、吸烟、运动与AS发生相关。建议除加强定期常规体检,控制可改变的血压、血糖、血脂以外,加强生活方式管理,检测RDW-SD,针对性干预高危人群,减少危险因素,降低AS的发生率亦为重要。

Objective To investigate the prevalence and risk factors of atherosclerotic(AS)in healthy people by measuring cardio-ankle vascular index(CAVI).Methods CAVI,body mass index,blood pressure,blood glucose,blood lipid,uric acid,hemoglobin(HGB)and erythrocyte distribution width(RDW-SD)were measured.To investigate the history of hypertension and diabetes,smoking and exercise.According to the results of CAVI,they were divided into AS group,critical group and non-AS Group.the baseline data between groups were statistically analyzed and multivariate regression analysis was performed to study the risk factors of arteriosclerosis.Results The age,systolic blood pressure,diastolic blood pressure,fasting blood glucose,cholesterol and erythrocyte distribution width in AS group were higher than those in critical group,and the detection rate of CAVI in smoking group was higher than that in non-smoking group,and the detection rate of CAVI in critical group was higher than that in non-smoking group.The detection rate of CAVI in the non-exercise group was higher than that in the exercise group(P<0.05).Age,sex,BMI,blood pressure,blood glucose and RDW-SD were independent risk factors for AS,among which blood pressure had the greatest effect on arteriosclerosis(oR=4.089).Conclusion Many factors are related to the occurrence of AS,and there are many reports about age,sex,blood pressure,blood cholesterol and blood sugar.It is found that RDW-SD,smoking and exercise are related to the occurrence of AS.It is suggested that in addition to strengthening regular routine physical examination and controlling changeable blood pressure,blood glucose and blood lipids,it is also important to strengthen lifestyle management,detect RDW-SD,targeted intervention in high-risk population,reduce risk factors and reduce the incidence of AS.