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硼替佐米联合地塞米松治疗多发性骨髓瘤的疗效及安全性分析 被引量:6

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摘要 目的:探究硼替佐米联合地塞米松治疗多发性骨髓瘤的疗效及安全性。方法:选取我院2017年1月—2018年6月多发性骨髓瘤患者78例,按随机数字表法分为对照组(n=39)与观察组(n=39)。对照组给予地塞米松、吡柔比星、长春新碱、沙利度胺治疗,观察组给予硼替佐米联合地塞米松治疗。观察比较两组疗效、不良反应发生情况及化疗前后血钙水平、骨痛程度、血磷水平。结果:观察组总有效率(92.31%)与对照组(56.41%)相比,明显提高(P<0.05);化疗3个疗程后两组血钙水平、骨痛程度、血磷水平低于化疗前(P<0.05),观察组血钙水平、骨痛程度、血磷水平低于对照组(P<0.05);观察组白细胞下降、血小板下降发生率低于对照组(P<0.05)。结论:硼替佐米联合地塞米松治疗多发性骨髓瘤,可明显降低患者血钙水平、血磷水平,改善骨痛程度,疗效显著,安全性高。
出处 《医学理论与实践》 2020年第1期65-66,共2页 The Journal of Medical Theory and Practice
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