基于中医传承辅助平台探讨黄丽娟教授治疗慢性心力衰竭用药规律

Analysis of the Law of Huang Lijuan in Treating Chronic Heart Failure Based on Auxiliary Platform of Traditional Chinese Medicine

目的基于中医传承辅助平台分析黄丽娟教授治疗慢性心力衰竭用药规律。方法采集黄丽娟教授治疗慢性心力衰竭的门诊医案,运用中医传承辅助平台建立医案数据库,基于该软件的集成规则分析、改进互信息法、复杂系统熵聚类分析等数据挖掘方法,对黄丽娟教授治疗慢性心力衰竭的用药规律进行总结。结果整理出黄丽娟教授治疗慢性慢性心力衰竭的方剂共114首,共使用中药108味,其中使用频率以生黄芪、丹参、茯苓最多。药物四气以温性为主;药物五味中甘味最多;药物归经,以肝经、心经频率最高。常用对药组合32组;常用角药组合48组,演化得到药物关联度网络展示图1幅,核心组合6组,新处3首。结论黄丽娟教授治疗慢性心力衰竭以益气温阳、活血利水为基本治法,兼以泻肺利水、补益心阴。

Objective To analyze the prescription of Huang Lijuan in the treatment of chronic heart failure based on the TCM inheritance platform.Methods Professor Huang Lijuan's outpatient medical treatment for chronic heart failure was collected,and the medical record database was established by using the Chinese medicine inheritance auxiliary platform.Based on the software's integrated rule analysis,improved mutual information method,complex system entropy clustering analysis and other data mining methods,Professor Huang Lijuan summed up the treatment of chronic heart failure.Results A total of 114 prescriptions for treating chronic cardiac insufficiency were prepared by Professor Huang Lijuan.A total of 108 Chinese herbal medicines were used.The frequency of use was the highest in jaundice,salvia,and medlar.The four gases of the drug are mainly temperate;the drug has the most sweet taste in the five flavors;the drug is followed by the liver,and the heart rate is the highest.There are 32 groups of commonly used drug combinations;48 groups of common horn drugs are combined,and the map shows the drug association degree network,6 core groups,and 3 new sites.Conclusions Professor Huang Lijuan is treating the chronic heart failure with the benefits of temperature and yang,promoting blood circulation and diuresis as the basic treatment,and also relies on diarrhea and lung water and replenishing heart and yin.