中医疏肝化瘀法对下肢动脉血管介入术后再狭窄的疗效及对血流动力学影响

Effect of “soothing the liver and resolving stasis” therapy on restenosis after lower extremity arterial intervention and on hemodynamics

目的探究中医疏肝化瘀法对下肢动脉血管介入术后再狭窄的疗效及对血流动力学影响。方法选取2016年3月-2018年5月收治的110例行下肢动脉血管介入术后再狭窄患者作为研究对象,按照随机数字法分为观察组54例和对照组56例,对照组采用常规西医治疗,观察组在对照组基础上采用中医疏肝化瘀法。观察并记录两组病例治疗后临床疗效及治疗前后血流动力学变化情况。结果观察组治疗后总有效率明显高于对照组同期(P<0.05),差异具有统计学意义。治疗3个月及6个月后,观察组股总动脉血流速度、股浅动脉血流速度及胫后动脉血流速度明显快于对照组(P<0.05),差异具有统计学意义。结论中医疏肝化瘀法有利于改善下肢动脉血管介入术后再狭窄患者临床症状与体征,有利于增加术后血管远期通畅率,减少术后再狭窄的发生,提高了患者的生存质量。

Objective To investigate the effect of“soothing the liver and resolving stasis”therapy on restenosis after lower extremity arterial intervention and on hemodynamics.Methods A total of 110 patients with restenosis after lower extremity arterial intervention admitted to our hospital from March,2016 to May,2018 were randomly divided into the observation group(n=54)and the control group(n=56)by the random number table.The control group was given conventional treatment and the observation group was additionally given“soothing the liver and resolving stasis”therapy.Clinical efficacy and hemodynamics in both groups were observed.Results The total effective rate in the observation group was significantly higher than that in the control group(P<0.05).At the end of the 3rd and 6th month of the treatment,the common femoral artery blood flow velocity,superficial femoral artery blood flow velocity and posterior tibial artery blood flow velocity in the observation group were faster than those in the control group(P<0.05),with significance.Conclusions“Soothing the liver and resolving stasis”therapy is beneficial to the improvement of the clinical symptoms and signs in patients with restenosis after lower extremity arterial intervention,which can increase the long-term patency rate of postoperative blood vessels,reduce the occurrence of postoperative restenosis and improve the quality of life.