奥曲肽联合乌司他丁治疗急性胰腺炎的疗效

The therapeutic effect of octreotide combined with ulinastatin in the treatment of acute pancreatitis

目的:观察奥曲肽联合乌司他丁治疗急性胰腺炎的疗效。方法:2018年2月-2019年2月收治急性胰腺炎患者80例,按治疗方法不同分为两组,各40例。试验组应用奥曲肽联合乌司他丁治疗;对照组单纯应用奥曲肽治疗。比较两组治疗效果。结果:两组治疗前血淀粉酶阳性率、尿淀粉酶阳性率、C反应蛋白水平比较,差异无统计学意义(P>0.05);试验组治疗后血淀粉酶阳性率、尿淀粉酶阳性率、C反应蛋白水平均显著低于对照组,差异有统计学意义(P<0.05);试验组治疗总有效率显著高于对照组,并发症发生率显著低于对照组,差异有统计学意义(P<0.05)。结论:奥曲肽联合乌司他丁治疗急性胰腺炎疗效显著。

Objective:To observe the therapeutic effect of octreotide combined with ulinastatin in the treatment of acute pancreatitis.Methods:80 patients with acute pancreatitis were selected from February 2018 to February 2019.They were divided into two groups with 40 cases in each group according to different treatment methods.The experimental group was treated with octreotide and ulinastatin,while the control group was treated with octreotide only.We compared the therapeutic effect of the two groups.Results:There was no significant difference in blood amylase positive rate,urinary amylase positive rate and C-reactive protein level between groups before treatment(P>0.05).The levels of serum amylase,urine amylase and C-reactive protein in the experimental group were significantly lower than those in the control group after treatment,and the differences were statistically significant(P<0.05).The total effective rate of the experimental group was significantly higher than that of the control group,and the complication rate was significantly lower than that of the control group;the differences were statistically significant(P<0.05).Conclusion:Octreotide combined with ulinastatin is effective in the treatment of acute pancreatitis.