普米克令舒、万托林联合甲强龙治疗小儿毛细支气管炎的临床效果

Clinical effect of pulmicort respules, ventolin combined with methylprednisolone in the treatment of children with bronchiolitis

目的探讨普米克令舒、万托林联合甲强龙治疗小儿毛细支气管炎的临床效果。方法选取我院收治的60例毛细支气管炎患儿,采用计算机随机抽样法将其分为常规组(n=30,普米克令舒+万托林)和联合组(n=30,普米克令舒+万托林+甲强龙)。比较两组的治疗效果。结果治疗后,联合组的治疗总有效率、用力肺活量、第一秒用力呼气容积均明显高于常规组(P<0.05);联合组的咳嗽、喘憋、肺啰音、哮鸣音消失时间及白细胞介素-6、肿瘤坏死因子-α水平均明显优于常规组(P<0.05)。两组的不良反应总发生率比较,差异无统计学意义(P>0.05)。结论普米克令舒、万托林联合甲强龙治疗小儿毛细支气管炎的临床效果显著,且安全性高。

Objective To explore the clinical effect of pulmicort respules,ventolin combined with methylprednisolone in the treatment of children with bronchiolitis.Methods A total of 60 children with bronchiolitis admitted in our hospital were divided into conventional group(n=30,pulmicort respules+ventolin)and combined group(n=30,pulmicort respules+ventolin+methylprednisolone)by computer random sampling.The clinical effects of the two groups were compared.Results After treatment,the total effective rate,forced vital capacity and forced expiratory volume in the first second in the combined group were significantly higher than those in the conventional group(P<0.05);the disappearance time of cough,wheezing,rale and wheezing,the levels of IL-6 and TNF-αin the combined group were significantly better than those in the conventional group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Pulmicort respules,ventolin combined with methylprednisolone in the treatment of children with bronchiolitis has a significant clinical effect,with high security.