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结肠癌患者NLR和PLR水平与淋巴结转移的关系 被引量:6

Relationship between NLR and PLR levels and lymph node metastasis in patients with colorectal cancer
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摘要 探讨结肠癌患者中性粒细胞淋巴细胞比(NLR)、血小板淋巴细胞比(PLR)与淋巴结转移的关系。2016年1月—2018年11月结肠癌233例,分析NLR、PLR与临床病理特征的关系。结果显示,低分化、有淋巴结转移、浸润深度T3~T4、TNM分期Ⅲ~Ⅳ期、有脉管侵犯患者NLR≥1.60的比例分别为76.14%、79.59%、63.21%、73.87%和75.76%,明显高于中高分化、无淋巴结转移、浸润深度T1~T2、TNM分期Ⅰ~Ⅱ期、无脉管侵犯患者(P<0.05);肿瘤直径≥5cm、低分化、有淋巴结转移、浸润深度T3~T4、TNM分期Ⅲ~Ⅳ期、有脉管侵犯患者PLR≥130.30的比例分别为71.88%、84.09%、83.67%、67.36%、80.18%和81.82%朋显高于肿瘤直径<5cm、中高分化、无淋巴结转移、浸润深度T1~T2、TNM分期Ⅰ~Ⅱ期、无脉管侵犯患者(P<0.05);Logistic回归分析结果显示:分化程度、浸润深度、NLR和PLR是结肠癌患者发生淋巴结转移的独立影响因素(OR=2.018、2.748、1.994和1.919,P<0.05)。结果表明,结肠癌患者术前NLR、PLR与临床病理特征有一定关系同时是结肠癌患者发生淋巴结转移的独立影响因素。
作者 范岭 崔国平 石国豪 FAN Ling;CUI Guo-ping;SHI Guo-hao
出处 《中国现代普通外科进展》 CAS 2019年第9期744-746,共3页 Chinese Journal of Current Advances in General Surgery
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