帕金森病患者服药依从性与心理社会适应及家庭关怀度的相关性

Correlations of medication compliance, psychosocial adaptation and family care among patients with Parkinson’s disease

目的了解帕金森病患者服药依从性、心理社会适应及家庭关怀度的现状及其相关性,探讨家庭关怀度在心理社会适应与服药依从性间的中介作用。方法采用一般资料调查表、服药依从性评估量表、帕金森病患者心理社会适应量表、家庭关怀度指数问卷对215例帕金森病患者进行调查。结果帕金森病患者服药依从性总分(9.76±3.59)分,心理社会适应总分为(83.34±14.93)分,家庭关怀度总分为(6.86±2.44)分。帕金森病患者服药依从性与家庭关怀度呈正相关(r=0.597,P<0.01),与心理社会适应也呈正相关(r=0.710,P<0.01)。家庭关怀度的亲密度维度在心理社会适应的自我效能维度、焦虑/抑郁维度和社会支持维度对服药依从性的影响中起中介作用,中介效应占总效应的21.7%。结论心理社会适应的自我效能、焦虑/抑郁和社会支持可直接或间接通过家庭关怀度的亲密度影响帕金森病患者的服药依从性,患者建立良好的心理社会适应能力和正常的家庭功能有助于患者服药依从性的提升。

Objective To explore correlations of medication compliance,psychosocial adaptation and family care and probe into the mediating role of family care in psychosocial adaptation and medication compliance.Methods A total of 215 patients with Parkinson's disease were enrolled in the investigation using convenience sampling method and were assessed with self-designed general information questionnaire,medication compliance assessment scale,psychosocial adjustment scale for Parkinsonxs disease(PAS),family care index questionnaire(Family APGAR Index,APGAR)and modified Hoehn&Yahr grading scale(H-Y).Results The total score of medication compliance for patients with Parkinsonxs disease was 9.76±3.59.The scores of psychosocial adaptation and family care were 83.34±14.93 and 6.86±2.44,respectively.The correlation between psychosocial adaptation and medication compliance was significantly positive(r=0.597,P<0.01)and medication compliance was positively correlated with family care(r=0.710,P<0.01).In the mediating effect test,intimacy dimension of family care was the intermediate variable of anxiety/depression dimension,self-efficiency dimension and social support dimension of psychosocial adaptation,with the intermediary rate of 21.7%.Conclusions Family care plays a partial mediating role in psychosocial adaptation and medication compliance.Enhancing psychosocial adaptation and maintaining nonnal family functions can effectively improve patients' medication compliance.