RuSiNPs/SnO2复合膜修饰电极用于沙丁胺醇的检测

Research on Detection of Salbutamol Using RuSiNPs/SnO2 Complex Modified GCE

采用一步法制得三联吡啶钌(Ru(bpy)32+)复合的二氧化硅(SiO2)纳米粒子(RuSiNPs),并将其与氧化锡(SnO2)共同修饰在玻碳电极(GCE)表面,构建了一种高灵敏度的增敏型电化学发光(ECL)传感器,并将其应用于沙丁胺醇测定的研究。当一定量的沙丁胺醇加入到电解液之中后,ECL强度得到加强,且当沙丁胺醇浓度在10~5.0×104 nmol·L-1范围内时,增加的ECL强度与沙丁胺醇浓度的对数呈现很好的线性关系,检测限为3.2 nmol·L-1(S/N=3)。此方法在应用到实际样品中沙丁胺醇含量的测定时,具有很好的抗干扰能力,增加了电化学发光法在现实领域的应用潜力。

The Ru(bpy)32+immobilized SiO2 nanoparticles(RuSiNPs)were successfully prepared through a one-step reaction.After that,the RuSiNPs and SnO2 were co-modified on GCE surface to construct a highly sensitive electrochemiluminescence(ECL)sensor for salbutamol.When a certain amount of salbutamol was present in the electrolyte,the ECL intensity was enhanced and showed a good correlation to salbutamol concentration in the range 10-5.0×104 nmol·L-1,with a detection limit of 3.2 nmol·L-1(S/N=3).Furthermore,the proposed ECL sensor exhibited an excellent anti-interference ability when it was applied for salbutamol detection in real samples.It significantly increased the application potential of ECL method in real-world.