摘要
Single-cell RNA-seq,with its capability to align cells of continuously changed status by pseudo-time reconstruction,has greatly revolutionized the understanding of cell fate transition during embryo development(Shapiroetal.,2013;Hoppeetal.,2014).
基金
the National Key Basic Research and Development Program of China(2018YFA0108000,2018YFA0800100,2017YFA0102700,2015CB964500,and 2014CB964804 to N J.
2018YFA0107201 to G.P.)
the‘Strategic Priority Research Program’of the Chinese Academy of Sciences(XDA16020501 to N.J.
XDA16020404 to G.P.)
the National Natural Science Foundation of China(31871456 to G.P.
3166U 43042,91519314,31630043,31571513,and 31430058 to N.j.)
Shanghai Natural Science Foundation(18ZR1446200)
Science and Technology Planning Project of Guangdong Province(2017B030314056)
Frontier Research Program of Guangzhou Regenerative Medicine and Health Guangdong Laboratory(2018GZR110105013).
