基于响应面法的重金属螯合剂前体物合成条件优化研究

Optimization of synthesis process of heavy metal chelating agent precursor by response surface methodology

以小分子的乙二胺与环氧氯丙烷为原料,以黏度为考察对象,对高分子重金属螯合剂的前体物合成条件进行优化。采用单因素实验确定黏度的主要影响因素,然后采用响应面法对制备条件进行优化。结果表明:(1)拟合的模型回归项显著而失拟项不显著,拟合性良好。(2)最佳制备条件为环氧氯丙烷和乙二胺摩尔比1.1、反应温度82.8℃、反应时间9.2h、NaOH和乙二胺摩尔比1.2。(3)产物傅立叶红外光谱表明,特征官能团的存在证明了前体物的生成。(4)利用前体物进一步合成了螯合剂,该螯合剂的Pb去除和稳定效果明显优于市售螯合剂。

The precursor of new macromolecular heavy metal chelating agent was synthesized using amine and epichlorohydrin.Taking the viscosity as the indicator,effects of different factors were investigated and the optimal reaction conditions were determined by response surface methodology.The results showed that:(1)the regression of the model was significant and lack of fit was not significant,which indicated the model fit the experimental data well.(2)The determined optimal synthesis parameters were molar ratio of epichlorohydrin to amine of 1.1,temperature of 82.8℃,reaction time of 9.2 hours,molar ratio of sodium hydroxide to amine of 1.2,respectively.(3)The synthetized precursor was analyzed by FTIR and it was further used for heavy metal chelating agent synthesis.(4)Heavy metal chelating agent synthesized with the precursor was shown to have better removal and stabilization effect than that of present commercial ones.