整合酶抑制剂在HIV感染全程管理中的应用优势

Application advantage of integrase inhibitors in full processing strategy during HIV infection

随着HIV抗反转录病毒治疗(antiretroviral therapy, ART)的研究进展,ART时机的不断提前以及ART药物的迅速发展,HIV感染者可以获得期望寿命。现在对HIV感染者的关注不仅仅在于AIDS本身,更多应该关注HIV感染者的合并症,甚至心理疾病。中华医学会发布的《艾滋病诊疗指南(2018版)》提出全程管理的概念,而整合酶抑制剂在HIV感染全程管理的多个环节中优势显著,本文就其在全程管理中的地位以及应用展开讨论。

Life expectancy has been available to HIV patients following the progress of antiretroviral therapy(ART)research,advance of ART timing and development of ART drugs.Nowadays,in addition to AIDS itself,more attention should be paid to the complications and even psychological diseases of HIV patients.In the Chinese Medical Association Guidelines for Diagnosis and Treatment of AIDS in 2018,the concept of full processing management was proposed,and integrase inhibitors show a significant benefit in multiple aspects of full processing management for HIV infection.This article discusses the status and application of integrase inhibitors for the full processing management of HIV infection.