雌三醇乳膏联合甲硝唑治疗萎缩性阴道炎患者的临床价值分析

Clinical Value of Estriol Cream Combined with Metronidazole in the Treatment of Atrophic Vaginitis

目的:探讨雌三醇软膏联合甲硝唑治疗萎缩性阴道炎患者的临床价值。方法:将88例萎缩性阴道炎患者随机纳入甲组44例、乙组44例。其中甲组为甲硝唑单药治疗,乙组为雌三醇软膏联合甲硝唑治疗,比较两组总有效率、阴道健康及炎症评分、总不良反应率。结果:甲组总有效率为81.82%、总不良反应率为27.28%,乙组则为95.45%、9.09%,各数据间比较有意义(P<0.05)。乙组阴道健康评分、阴道炎症评分明显优于甲组,各数据间比较有意义(P<0.05)。结论:在萎缩性阴道炎患者治疗过程中,雌三醇软膏联合甲硝唑治疗方式,不仅可提高治疗总有效率,还可在改善患者阴道健康评分、炎症评分的同时,预防或减少不良反应的出现。

Objective: To investigate the clinical value of estriol ointment combined with metronidazole in the treatment of atrophic vaginitis. Methods: 88 patients with atrophic vaginitis were randomly divided into group A(44 cases) and group B(44 cases). The patients in group A were treated with metronidazole alone, and the patients in group B were treated with estriol ointment combined with metronidazole. The total effective rate, vaginal health, inflammation score and total adverse reaction rate were compared between the two groups. Results: The total effective rate was 81.82% and the total adverse reaction rate was 27.28% in group A and 95.45% and 9.09% in group B, which was significant(P<0.05). The vaginal health score and vaginitis score of group B were significantly better than that of group A, and the data were significant(P<0.05). Conclusion: During the treatment of atrophic vaginitis patients, estriol ointment combined with metronidazole therapy can not only improve the total effective rate of treatment, but also prevent or reduce the occurrence of adverse reactions while improving the vaginal health score and inflammation score of patients.