320排CT双低冠状动脉MIP血管成像在阻塞性睡眠呼吸暂停综合征伴冠心病中的应用

The application of 320-slice CT "double-low" MIP imaging technique in obstructive sleep apnea syndrome with coronary heart disease

目的探讨320排CT双低(低管电压和低对比剂浓度)冠状动脉最大密度投影(MIP)成像在阻塞性睡眠呼吸暂停综合征(OSAS)伴冠状动脉粥样硬化性心脏病(冠心病)中的诊断价值。方法选取本院收治的OSAS伴冠心病患者40例,所有患者均行320排CT成像并于1个月内接受常规冠脉造影(CAG)检查,以CAG检查结果为参照,评价320排CT双低冠脉MIP成像在诊断OSAS伴冠心病的准确性。结果320排CT双低冠脉MIP成像在诊断OSAS伴冠脉病变的灵敏度、特异度、准确率、阳性预测值及阴性预测值分别为95.14%、94.43%、95.33%、83.62%、98.20%。受试者的心率为(65.20±4.79)次/min,剂量长度乘积(DLP)为(98.22±32.54)m Gy·cm,有效辐射剂量(ED)为(1.35±0.42)m Sv。结论320排CT双低冠状动脉MIP成像较常规CAG降低了辐射危险性剂量,所获图像在OSAS伴冠心病的临床诊断中具有较高参考价值。

Objective To evaluate the value of 320-slice computed tomography(CT)"doublelow"maximum density projection(MIP)imaging protocol(low tube voltage and low contrast agent concentration)in obstructive sleep apnea syndrome(OSAS)with coronary heart disease.Methods 40 cases of OSAS with coronary heart disease in our hospital were selected.All patients underwent 320-slice CT"double-low"MIP imaging and received conventional coronary angiography(CAG)within 1 month.With reference to CAG examination results,the accuracy of 320-slice CT"double low"MIP-imaging technique in diagnosing the Obstructive sleep apnea syndrome with coronary heart disease can be evaluated.Results The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of 320-slice CT"double-low"MIP imaging in the diagnosis of obstructive respiratory sleep disorder with coronary disease were 95.14%,94.43%,95.33%,83.62%,98.20%.respectively.The heart rate of testers was(65.20±4.79)bpm/min,the dose length product(DLP)was(98.22±32.54)m Gy·cm,and the effective radiation dose(ED)was(1.35±0.42)m Sv.Conclusions Compared with CAG,the 320-slice CT"doublelow"MIP imaging technique reduced doses of radiation while maintained the good quality of image.Therefore,this technique has high application value as a clinical diagnosis method to diagnose patients with obstructive respiratory sleep disorder and coronary heart disease.