右美托咪定抑制剖宫产麻醉寒颤最佳给药时机

The Best Time for Dexmedetomidine to Inhibit the Shivering of Cesarean Section Anesthesia

目的探讨右美托咪定抑制剖宫产麻醉寒颤最佳给药时机。方法将我院行剖宫产手术的产妇90例分为A组,B组和C组,A组产妇则麻醉前5 min给予生理盐水,B组产妇在麻醉前5 min给予其右美托咪定,C组产妇则进行蛛网下腔给药后,让患者躺平即可给予右美托咪定,记录两组产妇不同时间段的血流动力学数据以及最终的寒颤发生情况。结果A组0级与B组、C组0级相比较时其差异具有统计学意义(P<0.05),表明A组寒颤未发生率相对较低。而A组1级、2级、3级以及4级均与B组、C组的1级、2级、3级以及4级比较其差异无统计学意义(P>0.05)。结论通过本次研究发现,右美托咪定在抑制麻醉后寒颤方面确实具有较好的效果,但是在研究中也发现,无论是在麻醉前给药还是在麻醉后立即给药产妇的寒颤发生情况并无明显的变化,不过两组产妇的相关血流动力学仍存在些许差异,是否受到用药时间的影响仍然需要进行较大数量的研究以证实。

Objective To explore the best time to administer dexmedetomidine to suppress anaesthetic chills in cesarean section.Methods Our hospital cesarean delivery operation of maternal 90 cases were divided into group A and group B and group C,group A maternal 5 min before anesthesia has given normal saline,group B maternal 5 min before anesthesia given the right beautiful mi set,maternal group C is for web after inferior vena to medicine,let the victim lie flat can give the right microphones set,two groups of women from different periods of hemodynamic data and the final chills is happening.Results The grade 0 difference between group A,group B and group C was statistically significant(P<0.05),indicating that the incidence of chills in group A was relatively low.However,grade 1,2,3 and 4 in group A were not significantly different from grade 1,2,3 and 4 in group B and C(P>0.05).Conclusion This study found that dexmedetomidine in inhibition of anesthesia chills aspect really has a good effect,but also in the study found that both before anesthesia administration and immediately after the anesthetic drug delivery of maternal chills is no obvious change is happening,but two groups of maternal related hemodynamics still there are some differences,whether received the influence of the medication time still a larger number of studies are needed to confirm.