大麻二酚添加治疗儿童难治性癫痫的研究现状

Research status on the treatment of refractory epilepsy in children by Cannabidiol as adjunctive therapy

近20多年,新型抗癫痫药物不断问世,但难治性癫痫患者的比例并无显著降低。因此,寻求一种可以有效减少惊厥发作,且不良反应相对较少的药物成为亟待解决的问题。近年来,以大麻为基础治疗癫痫的方法引起了广泛关注,大麻提纯物大麻二酚可减少难治性癫痫患儿的发作,现将研究现状作一综述。

In the past 20 years,new anti-epileptic drugs have been constantly developed,but the percentages of patients who suffer from refractory epilepsy have not been significantly decreased.Therefore,to find out a drug that can effectively reduce seizures with relatively fewer side effects has become an urgent issue.In recent years,the treatment of epilepsy based on Cannabis has drawn great public attention.Cannabidiol,which is purified from Cannabis,can relieve refractory epilepsy in children.The present findings of research are summarized in this paper.