基于人体头部模型的经颅磁刺激反向线圈研究

Study on Reverse Coil for Transcranial Magnetic Stimulation Based on Human Head Model

目的设计了一种新型的反向线圈以提高八字形线圈的聚焦性,同时衰减八字形线圈在头皮处产生的电场强度,减少对人体头部表面的刺激。方法根据反向线圈具有可变的高度和角度的特点,基于真实头部模型,对不同高度、角度和尺寸的反向线圈分别从电场强度、刺激深度及聚焦性3个方面进行分析,并与八字形线圈分析结果进行比较。结果选用合适参数的反向线圈,在头皮处产生的电场强度比八字形线圈减少了34.55%,刺激深度增加了1.6%,聚焦性提高了31.3%。结论使用合适的反向线圈可以减少八字形线圈对头皮处的影响,并提高聚焦性。

Objective To improve the focality of traditional figure-8 coil and reduce the electric field strength on the scalp of human scalp in transcranial magnetic stimulation(TMS),a new coil which called reverse coil was designed.Methods The reverse coil had variable heights and angles.The electric field intensity,the stimulation depth and the focality induced by different heights,angles and sizes of reverse coils were analyzed based on human head model.Then they were compared with those of the figure-8 coil.Results The electric field intensity on the scalp for the reverse coil with suitable parameters decreased by 34.55%,the penetration depth increased by 1.6%,and the focality increased by 31.3%as compared with those of the figure-8 coil.Conclusion The reverse coil provides a flexible method to reduce the electric field intensity on the scalp and improve the focality.